Especially for diagnostic applications PolyAn is offering a broad range of functionalized microarray polymer slides. For reasons of reliability and bio-safety, patient-centric biomarker testing is always performed in single-use cartridges with a one-step process (sample in – result out). These cartridges should be disposable after use, so the materials of the cartridge should be non-hazardous and recyclable
PolyAn's Polymer Slides are comprised of a low auto fluorescence plastic. The material is highly robust against breakage making it the material of choice when working with hazardous materials. It is suitable for injection molding and hot embossing processes
The slides are produced with standard dimensions of 25 x 75 x 1 mm. Additionally, we offer the functionalization of your plastic including microfluidics with a surface modification that is tailored to your specific application. Please also have a look at our ProPlate, HybriWell and SecureSeal products that facilitate handling of slides
| Id |
Surface Modifications |
Product Dimensions |
Packaging Volume |
| 104 00 051 |
3D-Amino |
25 x 75 mm |
25 Slides/Box |
| 104 00 151 |
3D-Carboxy |
25 x 75 mm |
25 Slides/Box |
| 104 00 251 |
3D-Epoxy |
25 x 75 mm |
25 Slides/Box |
| 104 00 351 |
3D-Aldehyde |
25 x 75 mm |
25 Slides/Box |
| 104 00 451 |
3D-NHS1 |
25 x 75 mm |
25 Slides/Box |
| 104 00 551 |
3D-Thiol |
25 x 75 mm |
25 Slides/Box |
| 104 01 251 |
Poly-L-Lysin (covalently coated)2 |
25 x 75 mm |
25 Slides/Box |
| 104 01 351 |
3D-PDITC (Activated Amino)3 |
25 x 75 mm |
25 Slides/Box |
| 104 01 451 |
3D-Maleimide4 |
25 x 75 mm |
25 Slides/Box |
| 104 02 255 |
Streptavidin (covalently coated) |
25 x 75 mm |
25 Slides/Box |
| 104 03 255 |
Neutravidin (covalently coated) |
25 x 75 mm |
25 Slides/Box |
1) 3D-NHS functionalized slides are used for covalent immobilization of biomolecules. The NHS-ester react immediately with the NH2- terminus of biochemical species to form a covalent bond with the surface
2) Poly-L-Lysin surfaces are well suited for coupling of biochemical species. Especially, when the storage buffer contains glycerol Poly-L-Lysin surfaces are an interesting alternative to reactive matrices
3) 3D-PDITC (1,4-phenylenediiso-thiocyanate) activated amino groups react immediately with the NH2- terminus of biochemical species to form a covalent bond with the surface (420 kJ/mol)
4) 3D-Maleimide-surfaces for „click chemistry“ for oriented covalent coupling (immobilization) of thiolated biochemical species
PolyAn’s 3D-functionalised microarray Slides are functionalized with a three-dimensional (3D)-surface chemistry comprised of a long-chain polymer containing a defined number of reactive groups. This polymer is covalently linked to the surface of the slide.
Our MSE-technology gently binds the functional layer onto the surface without damaging the base substrate. The morphology of the functional surface and thus also the number of the reactive groups can be fine-tuned within a narrow range. This yields a number of advantages:
| Low fluorescence background |
Covalent binding of functional layer on the substrate without changing the initial autofluorescence |
| Low unspecific binding |
Combination of reactive functional groups with PolyAn antifouling matrix |
| Topography |
Tuneable surface
hydrophilicity / hydrophobicity (contact angle) |
| Uniform spot morphology |
Narrow variation of surface properties and homogeneous distribution of reactive groups |
| Optimal density and high accessibility of reactive groups |
Morphology and thickness of functional layer tailored to the desired application |
Technical specifications
Packaging
The slides are packaged in inert atmospheric boxes, with a capacity of 25 or 5 slides per box.
Storage
PolyAn’s slides are characterised by a long shelf-life when stored dry, at 4-8°C and protected from sunlight. All slides are packaged in boxes under Argon atmosphere to avoid contamination with particles. The Argon atmosphere also minimises degradation of the reactive surface through contact with air or humidity
